Topiramate: here's the fair price
This is what US pharmacies pay, on average, for topiramate. Use it to spot a fair cash price, and feel good about asking for one.
Topiramate 25 Mg Tablet
A fair cash price is usually this cost plus a dispensing fee. If your quote is many times higher, ask about a generic, another pharmacy, or a cash discount.
Ask for generic Topiramate 25 Mg Tablet. Pharmacies pay about $0.82 for 30. Ask your pharmacy for its cash price and compare it with your copay. A fair cash price is close to this cost plus a dispensing fee.
Source: CMS NADAC as of 2026-11-04. Ask your prescriber or pharmacist whether a generic is right for you.
Source: CMS NADAC weekly file as of 2026-11-04. Median across NDCs with the same description. Public domain.
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Every strength and form
| Product | Pharmacy cost | 30 count | Effective |
|---|---|---|---|
| TOPIRAMATE 25 MG TABLETGeneric | $0.03 per tablet or capsule | $0.82 | 10/21/2026 |
| TOPIRAMATE 50 MG TABLETGeneric | $0.04 per tablet or capsule | $1.19 | 10/21/2026 |
| TOPIRAMATE 100 MG TABLETGeneric | $0.06 per tablet or capsule | $1.78 | 10/21/2026 |
| TOPIRAMATE 200 MG TABLETGeneric | $0.11 per tablet or capsule | $3.27 | 10/21/2026 |
| TOPIRAMATE 15 MG SPRINKLE CAPGeneric | $0.23 per tablet or capsule | $6.94 | 10/21/2026 |
| TOPIRAMATE 25 MG SPRINKLE CAPGeneric | $0.24 per tablet or capsule | $7.34 | 10/21/2026 |
| TOPIRAMATE 25 MG/ML SOLUTIONGeneric | $1.59 per mL | n/a | 10/21/2026 |
| TOPIRAMATE ER 25 MG SPRINKL CAPGeneric | $2.23 per tablet or capsule | $66.90 | 10/21/2026 |
| TOPIRAMATE ER 50 MG SPRINKL CAPGeneric | $3.24 per tablet or capsule | $97.12 | 10/21/2026 |
| TOPIRAMATE ER 25 MG CAPSULEGeneric | $3.66 per tablet or capsule | $109.79 | 10/21/2026 |
| TOPIRAMATE 50 MG SPRINKLE CAPGeneric | $4.29 per tablet or capsule | $128.83 | 10/21/2026 |
| TOPIRAMATE ER 50 MG CAPSULEGeneric | $5.67 per tablet or capsule | $170.25 | 10/21/2026 |
| TOPIRAMATE ER 100 MG SPRINK CAPGeneric | $5.78 per tablet or capsule | $173.33 | 10/21/2026 |
| TOPIRAMATE ER 150 MG SPRINK CAPGeneric | $7.03 per tablet or capsule | $210.96 | 10/21/2026 |
| TOPIRAMATE ER 100 MG CAPSULEGeneric | $9.10 per tablet or capsule | $273.14 | 10/21/2026 |
| TOPIRAMATE ER 200 MG SPRINK CAPGeneric | $9.89 per tablet or capsule | $296.69 | 10/21/2026 |
| TOPIRAMATE ER 200 MG CAPSULEGeneric | $17.41 per tablet or capsule | $522.39 | 10/21/2026 |
Source: CMS NADAC, as of 2026-11-04. National average acquisition cost, not a retail quote.
Label basics
What it is used for (FDA label)
1 INDICATIONS AND USAGE Topiramate is indicated for: Epilepsy: initial monotherapy for the treatment of partial-onset or primary generalized tonic-clonic seizures in patients 2 years of age and older (1.1); adjunctive therapy for the treatment of partial-onset seizures, primary generalized tonic-clonic seizures, or seizures associated with Lennox- Gastaut syndrome in patients 2 years of age and older (1.2) Preventive treatment of migraine in patients 12 years of age and older (1.3) 1.1 Monotherapy Epilepsy Topiramate tablets are indicated as initial monotherapy for the treatment of partial-onset or primary generalized tonic-clonic seizures in patients 2 years of age and older. 1.2...
Common side effects (FDA label)
6 ADVERSE REACTIONS The following serious adverse reactions are discussed in more detail in other sections of the labeling: Acute Myopia and Secondary Angle Closure Glaucoma [see Warnings and Precautions (5.1)] Visual Field Defects [see Warnings and Precautions (5.2)] Oligohidrosis and Hyperthermia [see Warnings and Precautions (5.3)] Metabolic Acidosis [see Warnings and Precautions (5.4)] Suicidal Behavior and Ideation [see Warnings and Precautions (5.5)] Cognitive/Neuropsychiatric Adverse Reactions [see Warnings and Precautions (5.6)] Decrease of Bone Mineral Density [see Warnings and...
Drug interactions (from the label)
7 DRUG INTERACTIONS • Contraceptives: decreased contraceptive efficacy and increased breakthrough bleeding, especially at doses greater than 200 mg/day (7.4) • Monitor lithium levels if lithium is used with high-dose topiramate (7.7) 7.1 Antiepileptic Drugs Concomitant administration of phenytoin or carbamazepine with topiramate resulted in a clinically significant decrease in plasma concentrations of topiramate when compared to topiramate given alone. A dosage adjustment may be needed [see Dosage and Administration (2.1), Clinical Pharmacology (12.3) ]. Concomitant administration of valproic acid and topiramate has been associated with hypothermia and hyperammonemia with and without...
Warnings (from the label)
5 WARNINGS AND PRECAUTIONS Acute myopia and secondary angle closure glaucoma: can lead to permanent visual loss; discontinue topiramate as soon as possible (5.1) Visual field defects: consider discontinuation of topiramate (5.2) Oligohidrosis and hyperthermia: monitor decreased sweating and increased body temperature, especially in pediatric patients (5.3) Metabolic acidosis: baseline and periodic measurement of serum bicarbonate is recommended; consider dose reduction or discontinuation of topiramate if clinically appropriate (5.4) Suicidal behavior and ideation: antiepileptic drugs increase the risk of suicidal behavior or ideation (5.5) Cognitive/neuropsychiatric adverse reactions: use...
Source: FDA drug label via openFDA, label effective 2026-06-08. Full label on DailyMed. Excerpts are verbatim and truncated. Read the full label and ask your pharmacist.