Risperidone: here's the fair price
This is what US pharmacies pay, on average, for risperidone. Use it to spot a fair cash price, and feel good about asking for one.
Risperidone 0.25 Mg Tablet
A fair cash price is usually this cost plus a dispensing fee. If your quote is many times higher, ask about a generic, another pharmacy, or a cash discount.
Ask for generic Risperidone 0.25 Mg Tablet. Pharmacies pay about $1.13 for 30. Ask your pharmacy for its cash price and compare it with your copay. A fair cash price is close to this cost plus a dispensing fee.
Source: CMS NADAC as of 2026-11-04. Ask your prescriber or pharmacist whether a generic is right for you.
Source: CMS NADAC weekly file as of 2026-11-04. Median across NDCs with the same description. Public domain.
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Every strength and form
| Product | Pharmacy cost | 30 count | Effective |
|---|---|---|---|
| RISPERIDONE 0.25 MG TABLETGeneric | $0.04 per tablet or capsule | $1.13 | 10/21/2026 |
| RISPERIDONE 0.5 MG TABLETGeneric | $0.04 per tablet or capsule | $1.14 | 10/21/2026 |
| RISPERIDONE 1 MG TABLETGeneric | $0.04 per tablet or capsule | $1.16 | 10/21/2026 |
| RISPERIDONE 2 MG TABLETGeneric | $0.05 per tablet or capsule | $1.62 | 10/21/2026 |
| RISPERIDONE 3 MG TABLETGeneric | $0.07 per tablet or capsule | $2.21 | 10/21/2026 |
| RISPERIDONE 4 MG TABLETGeneric | $0.08 per tablet or capsule | $2.53 | 10/21/2026 |
| RISPERIDONE 1 MG/ML SOLUTIONGeneric | $0.47 per mL | n/a | 10/21/2026 |
| RISPERIDONE 0.5 MG ODTGeneric | $0.99 per tablet or capsule | $29.83 | 10/21/2026 |
| RISPERIDONE 1 MG ODTGeneric | $1.16 per tablet or capsule | $34.76 | 10/28/2026 |
| RISPERIDONE 2 MG ODTGeneric | $1.18 per tablet or capsule | $35.39 | 10/21/2026 |
| RISPERIDONE 4 MG ODTGeneric | $1.59 per tablet or capsule | $47.79 | 10/28/2026 |
| RISPERIDONE 3 MG ODTGeneric | $1.74 per tablet or capsule | $52.23 | 10/28/2026 |
| RISPERIDONE 0.25 MG ODTGeneric | $2.54 per tablet or capsule | $76.24 | 10/21/2026 |
| RISPERIDONE ER 25 MG VIALGeneric | $349.18 per tablet or capsule | $10,475.32 | 10/21/2026 |
| RISPERIDONE ER 37.5 MG VIALGeneric | $577.67 per tablet or capsule | $17,330.19 | 10/21/2026 |
| RISPERIDONE ER 50 MG VIALGeneric | $762.23 per tablet or capsule | $22,866.89 | 10/21/2026 |
Source: CMS NADAC, as of 2026-11-04. National average acquisition cost, not a retail quote.
Label basics
What it is used for (FDA label)
1 INDICATIONS AND USAGE Risperidone tablets are an atypical antipsychotic indicated for: Treatment of schizophrenia ( 1.1 ) As monotherapy or adjunctive therapy with lithium or valproate, for the treatment of acute manic or mixed episodes associated with Bipolar I Disorder ( 1.2 ) Treatment of irritability associated with autistic disorder ( 1.3 ) 1.1 Schizophrenia Risperidone tablets are indicated for the treatment of schizophrenia. Efficacy was established in 4 short-term trials in adults, 2 short-term trials in adolescents (ages 13 to 17 years), and one long-term maintenance trial in adults [see Clinical Studies (14.1) ] . 1.2 Bipolar Mania Monotherapy Risperidone tablets are indicated...
Common side effects (FDA label)
6 ADVERSE REACTIONS The following are discussed in more detail in other sections of the labeling: • Increased mortality in elderly patients with dementia-related psychosis [see Boxed Warning and Warnings and Precautions ( 5.1 )] • Cerebrovascular adverse events, including stroke, in elderly patients with dementia-related psychosis [see Warnings and Precautions ( 5.2 )] • Neuroleptic malignant syndrome [see Warnings and Precautions ( 5.3 )] • Tardive dyskinesia [see Warnings and Precautions ( 5.4 )] • Metabolic Changes (Hyperglycemia and diabetes mellitus, Dyslipidemia, and Weight Gain) [see...
Drug interactions (from the label)
7 DRUG INTERACTIONS Carbamazepine and other enzyme inducers decrease plasma concentrations of risperidone. Increase the risperidone tablets dose up to double the patient’s usual dose. Titrate slowly. ( 7.1 ) Fluoxetine, paroxetine, and other CYP 2D6 enzyme inhibitors increase plasma concentrations of risperidone. Reduce the initial dose. Do not exceed a final dose of 8 mg per day of risperidone tablets. ( 7.1 ) 7.1 Pharmacokinetic-related Interactions The dose of risperidone tablets should be adjusted when used in combination with CYP2D6 enzyme inhibitors (e.g., fluoxetine, and paroxetine) and enzyme inducers (e.g., carbamazepine) [see Table 18 and Dosage and Administration (2.5) ]. Dose...
Warnings (from the label)
5 WARNINGS AND PRECAUTIONS Cerebrovascular events, including stroke, in elderly patients with dementia-related psychosis: Risperidone tablets are not approved for use in patients with dementia-related psychosis ( 5.2 ) Neuroleptic Malignant Syndrome: Manage with immediate discontinuation of risperidone tablets and close monitoring. ( 5.3 ) Tardive dyskinesia: Consider discontinuing risperidone tablets if clinically indicated. ( 5.4 ) Metabolic Changes: Atypical antipsychotic drugs have been associated with metabolic changes that may increase cardiovascular / cerebrovascular risk. These metabolic changes include hyperglycemia, dyslipidemia, and weight gain. ( 5.5 ) Hyperglycemia and Diabetes...
Source: FDA drug label via openFDA, label effective 2026-06-25. Full label on DailyMed. Excerpts are verbatim and truncated. Read the full label and ask your pharmacist.