Progesterone: here's the fair price
This is what US pharmacies pay, on average, for progesterone. Use it to spot a fair cash price, and feel good about asking for one.
Progesterone 100 Mg Capsule
A fair cash price is usually this cost plus a dispensing fee. If your quote is many times higher, ask about a generic, another pharmacy, or a cash discount.
Ask for generic Progesterone 100 Mg Capsule. Pharmacies pay about $6.99 for 30. Ask your pharmacy for its cash price and compare it with your copay. A fair cash price is close to this cost plus a dispensing fee.
Source: CMS NADAC as of 2026-11-04. Ask your prescriber or pharmacist whether a generic is right for you.
Source: CMS NADAC weekly file as of 2026-11-04. Median across NDCs with the same description. Public domain.
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Every strength and form
| Product | Pharmacy cost | 30 count | Effective |
|---|---|---|---|
| PROGESTERONE 100 MG CAPSULEGeneric | $0.23 per tablet or capsule | $6.99 | 10/21/2026 |
| PROGESTERONE 200 MG CAPSULEGeneric | $0.41 per tablet or capsule | $12.32 | 10/21/2026 |
| PROGESTERONE 500 MG/10 ML VIALGeneric | $1.33 per mL | n/a | 10/21/2026 |
| PROGESTERONE 100 MG VAG INSERTGeneric | $8.95 per tablet or capsule | $268.43 | 10/21/2026 |
Source: CMS NADAC, as of 2026-11-04. National average acquisition cost, not a retail quote.
Label basics
What it is used for (FDA label)
INDICATIONS AND USAGE Progesterone capsules are indicated for use in the prevention of endometrial hyperplasia in nonhysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also indicated for use in secondary amenorrhea.
Common side effects (FDA label)
ADVERSE REACTIONS See BOXED WARNING , WARNINGS and PRECAUTIONS. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. In a multicenter, randomized, double-blind, placebo-controlled clinical trial, the effects of progesterone capsules on the endometrium was studied in a total of 875 postmenopausal women. Table 6 lists adverse experiences greater than or equal to 2 percent of women who...
Warnings (from the label)
WARNINGS See BOXED WARNING . 1. Cardiovascular disorders An increased risk of pulmonary embolism, deep vein thrombosis (DVT), stroke, and myocardial infarction has been reported with estrogen plus progestin therapy. Should any of these occur or be suspected, estrogen with progestin therapy should be discontinued immediately. Risk factors for arterial vascular disease (for example, hypertension, diabetes mellitus, tobacco use, hypercholesterolemia, and obesity) and/or venous thromboembolism (for example, personal history or family history of venous thromboembolism [VTE], obesity, and systemic lupus erythematosus) should be managed appropriately. a. Stroke In the Women’s Health Initiative...
Source: FDA drug label via openFDA, label effective 2025-05-16. Full label on DailyMed. Excerpts are verbatim and truncated. Read the full label and ask your pharmacist.