Paroxetine: here's the fair price
This is what US pharmacies pay, on average, for paroxetine. Use it to spot a fair cash price, and feel good about asking for one.
Paroxetine Hcl 20 Mg Tablet
A fair cash price is usually this cost plus a dispensing fee. If your quote is many times higher, ask about a generic, another pharmacy, or a cash discount.
Ask for generic Paroxetine Hcl 20 Mg Tablet. Pharmacies pay about $1.88 for 30. Ask your pharmacy for its cash price and compare it with your copay. A fair cash price is close to this cost plus a dispensing fee.
Source: CMS NADAC as of 2026-11-04. Ask your prescriber or pharmacist whether a generic is right for you.
Source: CMS NADAC weekly file as of 2026-11-04. Median across NDCs with the same description. Public domain.
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Every strength and form
| Product | Pharmacy cost | 30 count | Effective |
|---|---|---|---|
| PAROXETINE HCL 20 MG TABLETGeneric | $0.06 per tablet or capsule | $1.88 | 10/21/2026 |
| PAROXETINE HCL 10 MG TABLETGeneric | $0.06 per tablet or capsule | $1.90 | 10/21/2026 |
| PAROXETINE HCL 40 MG TABLETGeneric | $0.10 per tablet or capsule | $2.94 | 10/21/2026 |
| PAROXETINE HCL 30 MG TABLETGeneric | $0.10 per tablet or capsule | $2.97 | 10/21/2026 |
| PAROXETINE CR 25 MG TABLETGeneric | $0.40 per tablet or capsule | $11.94 | 10/21/2026 |
| PAROXETINE ER 25 MG TABLETGeneric | $0.40 per tablet or capsule | $11.94 | 10/21/2026 |
| PAROXETINE CR 37.5 MG TABLETGeneric | $0.44 per tablet or capsule | $13.18 | 10/21/2026 |
| PAROXETINE ER 37.5 MG TABLETGeneric | $0.44 per tablet or capsule | $13.18 | 10/21/2026 |
| PAROXETINE CR 12.5 MG TABLETGeneric | $0.48 per tablet or capsule | $14.47 | 10/21/2026 |
| PAROXETINE ER 12.5 MG TABLETGeneric | $0.48 per tablet or capsule | $14.47 | 10/21/2026 |
| PAROXETINE HCL 10 MG/5 ML SUSPGeneric | $1.40 per mL | n/a | 10/21/2026 |
| PAROXETINE MESYLATE 7.5 MG CAPGeneric | $2.64 per tablet or capsule | $79.31 | 10/21/2026 |
Source: CMS NADAC, as of 2026-11-04. National average acquisition cost, not a retail quote.
Label basics
What it is used for (FDA label)
1 INDICATIONS AND USAGE Paroxetine tablets are indicated in adults for the treatment of: Major depressive disorder (MDD) Obsessive compulsive disorder (OCD) Panic disorder (PD) Social anxiety disorder (SAD) Generalized anxiety disorder (GAD) Posttraumatic stress disorder (PTSD) Paroxetine is a selective serotonin reuptake inhibitor (SSRI) indicated in adults for the treatment of ( 1 ): Major Depressive Disorder (MDD) Obsessive Compulsive Disorder (OCD) Panic Disorder (PD) Social Anxiety Disorder (SAD) Generalized Anxiety Disorder (GAD) Posttraumatic Stress Disorder (PTSD)
Common side effects (FDA label)
6 ADVERSE REACTIONS The following adverse reactions are included in more detail in other sections of the prescribing information: Hypersensitivity reactions to paroxetine [see Contraindications ( 4 )] Suicidal Thoughts and Behaviors [see Warnings and Precautions ( 5.1 )] Serotonin Syndrome [see Warnings and Precautions ( 5.2 )] Embryofetal Toxicity [see Warnings and Precautions ( 5.4 )] Increased Risk of Bleeding [see Warnings and Precautions ( 5.5 )] Activation of Mania/Hypomania [see Warnings and Precautions ( 5.6 )] Discontinuation Syndrome [see Warnings and Precautions ( 5.7 )] Seizures...
Drug interactions (from the label)
7 DRUG INTERACTIONS Table 9 presents clinically significant drug interactions with paroxetine. Table 9 Clinically Significant Drug Interactions with Paroxetine Monoamine Oxidase Inhibitors (MAOIs) Clinical Impact The concomitant use of SSRIs, including paroxetine, and MAOIs increases the risk of serotonin syndrome. Intervention Paroxetine is contraindicated in patients taking MAOIs, including MAOIs such as linezolid or intravenous methylene blue [see Dosage and Administration ( 2.5 ), Contraindications ( 4 ), Warnings and Precautions ( 5.2 )] . Examples selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue Pimozide and Thioridazine Clinical Impact Increased...
Warnings (from the label)
5 WARNINGS AND PRECAUTIONS Serotonin Syndrome: Increased risk when co-administered with other serotonergic agents, but also when taken alone. If occurs, discontinue paroxetine and serotonergic agents and initiate supportive measures. ( 5.2 ) Embryofetal Toxicity: May cause fetal harm. Meta-analyses of epidemiological studies have shown increased risk (less than 2-fold) of cardiovascular malformations with exposure during the first trimester. ( 5.4 , 8.1 ) Increased Risk of Bleeding: Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs, other antiplatelet drugs, warfarin, and other anticoagulant drugs may increase risk. ( 5.5 ) Activation of Mania/Hypomania: Screen patients for...
Source: FDA drug label via openFDA, label effective 2026-08-11. Full label on DailyMed. Excerpts are verbatim and truncated. Read the full label and ask your pharmacist.