Metformin: here's the fair price
This is what US pharmacies pay, on average, for metformin. Use it to spot a fair cash price, and feel good about asking for one.
Metformin Hcl 500 Mg Tablet
A fair cash price is usually this cost plus a dispensing fee. If your quote is many times higher, ask about a generic, another pharmacy, or a cash discount.
Ask for generic Metformin Hcl 500 Mg Tablet. Pharmacies pay about $0.44 for 30. Ask your pharmacy for its cash price and compare it with your copay. A fair cash price is close to this cost plus a dispensing fee.
Source: CMS NADAC as of 2026-11-04. Ask your prescriber or pharmacist whether a generic is right for you.
Source: CMS NADAC weekly file as of 2026-11-04. Median across NDCs with the same description. Public domain.
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Every strength and form
| Product | Pharmacy cost | 30 count | Effective |
|---|---|---|---|
| METFORMIN HCL 500 MG TABLETGeneric | $0.01 per tablet or capsule | $0.44 | 10/21/2026 |
| METFORMIN HCL 1,000 MG TABLETGeneric | $0.02 per tablet or capsule | $0.70 | 10/21/2026 |
| METFORMIN HCL 850 MG TABLETGeneric | $0.02 per tablet or capsule | $0.73 | 10/21/2026 |
| METFORMIN HCL ER 500 MG TABLETGeneric | $0.03 per tablet or capsule | $0.85 | 10/21/2026 |
| METFORMIN HCL ER 750 MG TABLETGeneric | $0.05 per tablet or capsule | $1.52 | 10/21/2026 |
| METFORMIN ER 500 MG OSMOTIC TBGeneric | $0.19 per tablet or capsule | $5.67 | 10/21/2026 |
| METFORMIN ER 500 MG GASTRC-TBGeneric | $0.28 per tablet or capsule | $8.49 | 10/21/2026 |
| METFORMIN ER 1,000 MG OSM-TABGeneric | $0.31 per tablet or capsule | $9.35 | 10/21/2026 |
| METFORMIN ER 1,000 MG GASTR-TBGeneric | $0.34 per tablet or capsule | $10.11 | 10/21/2026 |
| METFORMIN HCL 500 MG/5 ML SOLNGeneric | $0.36 per mL | n/a | 10/21/2026 |
| METFORMIN HCL 625 MG TABLETGeneric | $12.53 per tablet or capsule | $375.80 | 02/25/2026 |
| METFORMIN HCL 750 MG TABLETGeneric | $14.61 per tablet or capsule | $438.15 | 02/25/2026 |
Source: CMS NADAC, as of 2026-11-04. National average acquisition cost, not a retail quote.
Label basics
What it is used for (FDA label)
1 INDICATIONS AND USAGE ZITUVIMET is a combination of sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, and metformin hydrochloride (HCl), a biguanide, indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. ( 1 ) Limitations of Use: ZITUVIMET is not recommended in patients with type 1 diabetes mellitus. ( 1 ) ZITUVIMET has not been studied in patients with a history of pancreatitis. ( 1 ) ZITUVIMET is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Limitations of Use ZITUVIMET is not recommended in patients with type 1 diabetes mellitus. ZITUVIMET has not been...
Common side effects (FDA label)
6 ADVERSE REACTIONS The following adverse reactions are also discussed elsewhere in the prescribing information: Lactic Acidosis [see Warnings and Precautions ( 5.1 )] Pancreatitis [see Warnings and Precautions ( 5.2 )] Heart Failure [see Warnings and Precautions ( 5.3 )] Acute Renal Failure [see Warnings and Precautions ( 5.4 )] Vitamin B12 Deficiency [see Warnings and Precautions ( 5.5 )] Hypoglycemia with Concomitant Use with Insulin or Insulin Secretagogues [see Warnings and Precautions ( 5.6 )] Hypersensitivity Reactions [see Warnings and Precautions ( 5.7 )] Severe and Disabling...
Drug interactions (from the label)
7 DRUG INTERACTIONS Table 4 presents clinically significant drug interactions with ZITUVIMET: Table 4: Clinically Significant Drug Interactions with ZITUVIMET Carbonic Anhydrase Inhibitors Clinical Impact: Carbonic anhydrase inhibitors frequently cause a decrease in serum bicarbonate and induce non-anion gap, hyperchloremic metabolic acidosis. Concomitant use of these drugs with ZITUVIMET may increase the risk for lactic acidosis. Intervention: Consider more frequent monitoring of these patients. Examples: Topiramate, zonisamide, acetazolamide or dichlorphenamide. Drugs that Reduce Metformin Clearance Clinical Impact: Concomitant use of drugs that interfere with common renal tubular...
Warnings (from the label)
5 WARNINGS AND PRECAUTIONS Lactic Acidosis: See boxed warning . ( 5.1 ) Pancreatitis: There have been postmarketing reports of acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis. If pancreatitis is suspected, promptly discontinue ZITUVIMET. ( 5.2 ) Heart Failure : Has been observed with two other members of the DPP-4 inhibitor class. Consider risks and benefits of ZITUVIMET in patients who have known risk factors for heart failure. Monitor patients for signs and symptoms. ( 5.3 ) Acute Renal Failure: Has been reported postmarketing, sometimes requiring dialysis. Before initiating ZITUVIMET and at least annually thereafter, assess renal function. ( 5.4...
Source: FDA drug label via openFDA, label effective 2026-08-12. Full label on DailyMed. Excerpts are verbatim and truncated. Read the full label and ask your pharmacist.