Lamotrigine: here's the fair price
This is what US pharmacies pay, on average, for lamotrigine. Use it to spot a fair cash price, and feel good about asking for one.
Lamotrigine 25 Mg Tablet
A fair cash price is usually this cost plus a dispensing fee. If your quote is many times higher, ask about a generic, another pharmacy, or a cash discount.
Ask for generic Lamotrigine 25 Mg Tablet. Pharmacies pay about $0.81 for 30. Ask your pharmacy for its cash price and compare it with your copay. A fair cash price is close to this cost plus a dispensing fee.
Source: CMS NADAC as of 2026-11-04. Ask your prescriber or pharmacist whether a generic is right for you.
Source: CMS NADAC weekly file as of 2026-11-04. Median across NDCs with the same description. Public domain.
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Every strength and form
| Product | Pharmacy cost | 30 count | Effective |
|---|---|---|---|
| LAMOTRIGINE 25 MG TABLETGeneric | $0.03 per tablet or capsule | $0.81 | 10/21/2026 |
| LAMOTRIGINE 100 MG TABLETGeneric | $0.05 per tablet or capsule | $1.45 | 10/21/2026 |
| LAMOTRIGINE 150 MG TABLETGeneric | $0.07 per tablet or capsule | $2.06 | 10/21/2026 |
| LAMOTRIGINE 200 MG TABLETGeneric | $0.08 per tablet or capsule | $2.40 | 10/21/2026 |
| LAMOTRIGINE 25 MG DISPER TABGeneric | $0.15 per tablet or capsule | $4.51 | 10/21/2026 |
| LAMOTRIGINE 5 MG DISPER TABLETGeneric | $0.15 per tablet or capsule | $4.59 | 10/21/2026 |
| LAMOTRIGINE ER 25 MG TABLETGeneric | $0.36 per tablet or capsule | $10.84 | 10/21/2026 |
| LAMOTRIGINE ER 50 MG TABLETGeneric | $0.55 per tablet or capsule | $16.54 | 10/21/2026 |
| LAMOTRIGINE ER 200 MG TABLETGeneric | $0.65 per tablet or capsule | $19.45 | 10/21/2026 |
| LAMOTRIGINE ER 100 MG TABLETGeneric | $0.67 per tablet or capsule | $20.01 | 10/21/2026 |
| LAMOTRIGINE ER 250 MG TABLETGeneric | $1.21 per tablet or capsule | $36.44 | 10/21/2026 |
| LAMOTRIGINE ER 300 MG TABLETGeneric | $1.28 per tablet or capsule | $38.29 | 10/21/2026 |
| LAMOTRIGINE ODT 25 MG TABLETGeneric | $1.28 per tablet or capsule | $38.39 | 10/21/2026 |
| LAMOTRIGINE ODT 50 MG TABLETGeneric | $1.33 per tablet or capsule | $39.75 | 10/21/2026 |
| LAMOTRIGINE ODT 100 MG TABLETGeneric | $1.59 per tablet or capsule | $47.69 | 10/21/2026 |
| LAMOTRIGINE ODT 200 MG TABLETGeneric | $1.79 per tablet or capsule | $53.56 | 10/21/2026 |
| LAMOTRIGINE ODT KIT (ORANGE)Generic | $9.50 per tablet or capsule | $285.04 | 10/21/2026 |
Source: CMS NADAC, as of 2026-11-04. National average acquisition cost, not a retail quote.
Label basics
What it is used for (FDA label)
1 INDICATIONS AND USAGE Lamotrigine orally disintegrating tablets are indicated for: Epilepsy, adjunctive therapy in patients aged 2 years and older : partial-onset seizures. primary generalized tonic-clonic (PGTC) seizures. generalized seizures of Lennox-Gastaut syndrome. ( 1.1 ) Epilepsy, monotherapy in patients aged 16 years and older : Conversion to monotherapy in patients with partial-onset seizures who are receiving treatment with carbamazepine, phenytoin, phenobarbital, primidone, or valproate as the single antiepileptic drug. ( 1.1 ) Bipolar disorder : Maintenance treatment of bipolar I disorder to delay the time to occurrence of mood episodes in patients treated for acute mood...
Common side effects (FDA label)
6 ADVERSE REACTIONS The following serious adverse reactions are described in more detail in the Warnings and Precautions section of the labeling: Serious Skin Rashes [see Warnings and Precautions (5.1) ] Hemophagocytic Lymphohistiocytosis [see Warnings and Precautions (5.2) ] Multiorgan Hypersensitivity Reactions and Organ Failure [see Warnings and Precautions (5.3) ] Cardiac Rhythm and Conduction Abnormalities [see Warnings and Precautions (5.4) ] Blood Dyscrasias [see Warnings and Precautions (5.5) ] Suicidal Behavior and Ideation [see Warnings and Precautions (5.6) ] Aseptic Meningitis...
Drug interactions (from the label)
7 DRUG INTERACTIONS Significant drug interactions with lamotrigine are summarized in this section. Uridine 5ยด-diphospho-glucuronyl transferases (UGT) have been identified as the enzymes responsible for metabolism of lamotrigine. Drugs that induce or inhibit glucuronidation may, therefore, affect the apparent clearance of lamotrigine. Strong or moderate inducers of the cytochrome P450 3A4 (CYP3A4) enzyme, which are also known to induce UGT, may also enhance the metabolism of lamotrigine. Those drugs that have been demonstrated to have a clinically significant impact on lamotrigine metabolism are outlined in Table 13. Specific dosing guidance for these drugs is provided in the Dosage and...
Warnings (from the label)
5 WARNINGS AND PRECAUTIONS Life-threatening serious rash and/or rash-related death: Discontinue at the first sign of rash, unless the rash is clearly not drug related. ( Boxed Warning , 5.1 ) Hemophagocytic lymphohistiocytosis: Consider this diagnosis and evaluate patients immediately if they develop signs or symptoms of systemic inflammation. Discontinue lamotrigine if an alternative etiology is not established. ( 5.2 ) Fatal or life-threatening hypersensitivity reaction: Multiorgan hypersensitivity reactions, also known as drug reaction with eosinophilia and systemic symptoms, may be fatal or life threatening. Early signs may include rash, fever, and lymphadenopathy. These reactions may...
Source: FDA drug label via openFDA, label effective 2026-04-22. Full label on DailyMed. Excerpts are verbatim and truncated. Read the full label and ask your pharmacist.