Glipizide: here's the fair price
This is what US pharmacies pay, on average, for glipizide. Use it to spot a fair cash price, and feel good about asking for one.
Glipizide 5 Mg Tablet
A fair cash price is usually this cost plus a dispensing fee. If your quote is many times higher, ask about a generic, another pharmacy, or a cash discount.
Ask for generic Glipizide 5 Mg Tablet. Pharmacies pay about $0.99 for 30. Ask your pharmacy for its cash price and compare it with your copay. A fair cash price is close to this cost plus a dispensing fee.
Source: CMS NADAC as of 2026-11-04. Ask your prescriber or pharmacist whether a generic is right for you.
Source: CMS NADAC weekly file as of 2026-11-04. Median across NDCs with the same description. Public domain.
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Every strength and form
| Product | Pharmacy cost | 30 count | Effective |
|---|---|---|---|
| GLIPIZIDE 5 MG TABLETGeneric | $0.03 per tablet or capsule | $0.99 | 10/21/2026 |
| GLIPIZIDE 10 MG TABLETGeneric | $0.04 per tablet or capsule | $1.28 | 10/21/2026 |
| GLIPIZIDE ER 5 MG TABLETGeneric | $0.08 per tablet or capsule | $2.28 | 10/21/2026 |
| GLIPIZIDE ER 2.5 MG TABLETGeneric | $0.10 per tablet or capsule | $2.95 | 10/21/2026 |
| GLIPIZIDE ER 10 MG TABLETGeneric | $0.13 per tablet or capsule | $3.76 | 10/21/2026 |
| GLIPIZIDE 2.5 MG TABLETGeneric | $1.25 per tablet or capsule | $37.45 | 10/21/2026 |
Source: CMS NADAC, as of 2026-11-04. National average acquisition cost, not a retail quote.
Label basics
What it is used for (FDA label)
INDICATIONS AND USAGE Glipizide Tablets USP are indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
Common side effects (FDA label)
ADVERSE REACTIONS In U.S. and foreign controlled studies, the frequency of serious adverse reactions reported was very low. Of 702 patients, 11.8% reported adverse reactions and in only 1.5% was glipizide discontinued. Hypoglycemia See PRECAUTIONS and OVERDOSAGE sections. Gastrointestinal Gastrointestinal disturbances are the most common reactions. Gastrointestinal complaints were reported with the following approximate incidence: nausea and diarrhea, one in seventy; constipation and gastralgia, one in one hundred. They appear to be dose-related and may disappear on division or reduction of...
Drug interactions (from the label)
Drug Interactions The hypoglycemic action of sulfonylureas may be potentiated by certain drugs including non-steroidal anti-inflammatory agents, some azoles, and other drugs that are highly protein bound, salicylates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, quinolones and beta-adrenergic blocking agents. When such drugs are administered to a patient receiving glipizide, the patient should be observed closely for hypoglycemia. When such drugs are withdrawn from a patient receiving glipizide, the patient should be observed closely for loss of control. In vitro binding studies with human serum proteins indicate that glipizide binds differently than...
Warnings (from the label)
WARNINGS SPECIAL WARNING ON INCREASED RISK OF CARDIOVASCULAR MORTALITY The administration of oral hypoglycemic drugs has been reported to be associated with increased cardiovascular mortality as compared to treatment with diet alone or diet plus insulin. This warning is based on the study conducted by the University Group Diabetes Program (UGDP), a long-term prospective clinical trial designed to evaluate the effectiveness of glucose-lowering drugs in preventing or delaying vascular complications in patients with non-insulin-dependent diabetes. The study involved 823 patients who were randomly assigned to one of four treatment groups ( Diabetes , 19, supp. 2:747-830, 1970). UGDP reported...
Source: FDA drug label via openFDA, label effective 2026-08-27. Full label on DailyMed. Excerpts are verbatim and truncated. Read the full label and ask your pharmacist.