Cyclobenzaprine: here's the fair price
This is what US pharmacies pay, on average, for cyclobenzaprine. Use it to spot a fair cash price, and feel good about asking for one.
Cyclobenzaprine 10 Mg Tablet
A fair cash price is usually this cost plus a dispensing fee. If your quote is many times higher, ask about a generic, another pharmacy, or a cash discount.
Ask for generic Cyclobenzaprine 10 Mg Tablet. Pharmacies pay about $0.52 for 30. Ask your pharmacy for its cash price and compare it with your copay. A fair cash price is close to this cost plus a dispensing fee.
Source: CMS NADAC as of 2026-11-04. Ask your prescriber or pharmacist whether a generic is right for you.
Source: CMS NADAC weekly file as of 2026-11-04. Median across NDCs with the same description. Public domain.
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Every strength and form
| Product | Pharmacy cost | 30 count | Effective |
|---|---|---|---|
| CYCLOBENZAPRINE 10 MG TABLETGeneric | $0.02 per tablet or capsule | $0.52 | 10/21/2026 |
| CYCLOBENZAPRINE 5 MG TABLETGeneric | $0.02 per tablet or capsule | $0.67 | 10/21/2026 |
| CYCLOBENZAPRINE 7.5 MG TABLETGeneric | $0.29 per tablet or capsule | $8.78 | 10/21/2026 |
| CYCLOBENZAPRINE ER 15 MG CAPGeneric | $1.18 per tablet or capsule | $35.45 | 10/21/2026 |
| CYCLOBENZAPRINE ER 30 MG CAPGeneric | $1.47 per tablet or capsule | $44.00 | 10/21/2026 |
Source: CMS NADAC, as of 2026-11-04. National average acquisition cost, not a retail quote.
Label basics
What it is used for (FDA label)
INDICATIONS AND USAGE Cyclobenzaprine hydrochloride tablets, USP are indicated as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions. Improvement is manifested by relief of muscle spasm and its associated signs and symptoms, namely, pain, tenderness, limitation of motion, and restriction in activities of daily living. Cyclobenzaprine hydrochloride tablets should be used only for short periods (up to 2 or 3 weeks) because adequate evidence of effectiveness for more prolonged use is not available and because muscle spasm associated with acute, painful musculoskeletal conditions is generally of short duration and...
Common side effects (FDA label)
ADVERSE REACTIONS Incidence of most common adverse reactions in the two double-blind*, placebo-controlled 5 mg studies (incidence of > 3% on cyclobenzaprine hydrochloride 5 mg): Cyclobenzaprine Hydrochloride 5 mg Cyclobenzaprine Hydrochloride 10 mg Placebo N = 464 N = 249 N = 469 Drowsiness 29% 38% 10% Dry Mouth 21% 32% 7% Fatigue 6% 6% 3% Headache 5% 5% 8% *Note: Cyclobenzaprine hydrochloride 10 mg data are from one clinical trial. Cyclobenzaprine hydrochloride 5 mg and placebo data are from two studies. Adverse reactions which were reported in 1% to 3% of the patients were: abdominal pain,...
Warnings (from the label)
WARNINGS Serotonin Syndrome The development of a potentially life-threatening serotonin syndrome has been reported with cyclobenzaprine hydrochloride when used in combination with other drugs, such as selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), tramadol, bupropion, meperidine, verapamil, or (MAO) inhibitors. The concomitant use of cyclobenzaprine hydrochloride with MAO inhibitors is contraindicated (see CONTRAINDICATIONS ). Serotonin syndrome symptoms may include mental status changes (e.g., confusion, agitation, hallucinations), autonomic instability (e.g., diaphoresis, tachycardia, labile blood...
Source: FDA drug label via openFDA, label effective 2026-05-20. Full label on DailyMed. Excerpts are verbatim and truncated. Read the full label and ask your pharmacist.