Clonidine: here's the fair price
This is what US pharmacies pay, on average, for clonidine. Use it to spot a fair cash price, and feel good about asking for one.
Clonidine Hcl 0.1 Mg Tablet
A fair cash price is usually this cost plus a dispensing fee. If your quote is many times higher, ask about a generic, another pharmacy, or a cash discount.
Ask for generic Clonidine Hcl 0.1 Mg Tablet. Pharmacies pay about $0.70 for 30. Ask your pharmacy for its cash price and compare it with your copay. A fair cash price is close to this cost plus a dispensing fee.
Source: CMS NADAC as of 2026-11-04. Ask your prescriber or pharmacist whether a generic is right for you.
Source: CMS NADAC weekly file as of 2026-11-04. Median across NDCs with the same description. Public domain.
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Every strength and form
| Product | Pharmacy cost | 30 count | Effective |
|---|---|---|---|
| CLONIDINE HCL 0.1 MG TABLETGeneric | $0.02 per tablet or capsule | $0.70 | 10/21/2026 |
| CLONIDINE HCL 0.2 MG TABLETGeneric | $0.03 per tablet or capsule | $1.01 | 10/21/2026 |
| CLONIDINE HCL 0.3 MG TABLETGeneric | $0.04 per tablet or capsule | $1.22 | 10/21/2026 |
| CLONIDINE HCL ER 0.1 MG TABLETGeneric | $0.22 per tablet or capsule | $6.71 | 10/21/2026 |
| CLONIDINE HCL 0.05 MG TABLETGeneric | $1.17 per tablet or capsule | $35.20 | 10/21/2026 |
| CLONIDINE 0.1 MG/DAY PATCHGeneric | $6.54 per tablet or capsule | $196.35 | 10/21/2026 |
| CLONIDINE 0.2 MG/DAY PATCHGeneric | $8.77 per tablet or capsule | $263.01 | 10/21/2026 |
| CLONIDINE 0.3 MG/DAY PATCHGeneric | $12.38 per tablet or capsule | $371.35 | 10/21/2026 |
| CLONIDINE HCL ER 0.17 MG TABGeneric | $15.21 per tablet or capsule | $456.37 | 10/21/2026 |
Source: CMS NADAC, as of 2026-11-04. National average acquisition cost, not a retail quote.
Label basics
What it is used for (FDA label)
INDICATIONS AND USAGE Clonidine hydrochloride tablets are indicated in the treatment of hypertension. Clonidine hydrochloride tablets may be employed alone or concomitantly with other antihypertensive agents.
Common side effects (FDA label)
ADVERSE REACTIONS Most adverse effects are mild and tend to diminish with continued therapy. The most frequent (which appear to be dose-related) are dry mouth, occurring in about 40 of 100 patients; drowsiness, about 33 in 100; dizziness, about 16 in 100; constipation and sedation, each about 10 in 100. The following less frequent adverse experiences have also been reported in patients receiving clonidine hydrochloride tablets, but in many cases patients were receiving concomitant medication and a causal relationship has not been established. Body as a Whole: Fatigue, fever, headache, pallor,...
Drug interactions (from the label)
Drug Interactions Clonidine may potentiate the CNS-depressive effects of alcohol, barbiturates or other sedating drugs. If a patient receiving clonidine hydrochloride is also taking tricyclic antidepressants, the hypotensive effect of clonidine may be reduced, necessitating an increase in the clonidine dose. If a patient receiving clonidine is also taking neuroleptics, orthostatic regulation disturbances (e.g., orthostatic hypotension, dizziness, fatigue) may be induced or exacerbated. Monitor heart rate in patients receiving clonidine concomitantly with agents known to affect sinus node function or AV nodal conduction, e.g., digitalis, calcium channel blockers, and beta-blockers. Sinus...
Warnings (from the label)
WARNINGS Withdrawal Patients should be instructed not to discontinue therapy without consulting their physician. Sudden cessation of clonidine treatment has, in some cases, resulted in symptoms such as nervousness, agitation, headache, and tremor accompanied or followed by a rapid rise in blood pressure and elevated catecholamine concentrations in the plasma. The likelihood of such reactions to discontinuation of clonidine therapy appears to be greater after administration of higher doses or continuation of concomitant beta-blocker treatment and special caution is therefore advised in these situations. Rare instances of hypertensive encephalopathy, cerebrovascular accidents and death have...
Source: FDA drug label via openFDA, label effective 2026-09-08. Full label on DailyMed. Excerpts are verbatim and truncated. Read the full label and ask your pharmacist.